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IJTM | Free Full-Text | Artificial Intelligence in ...

2021-11-12 · The huge advancement in Internet web facilities as well as the progress in computing and algorithm development, along with current innovations regarding high-throughput techniques, enable the scientific community to gain access to biological datasets, clinical data and several databases containing billions of pieces of information concerning scientific knowledge. Consequently, during the last ...

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GAMMA-RAY BURSTS: PROGRESS, PROBLEMS & …

2021-9-6 · The cosmological gamma-ray burst (GRB) phenomenon is reviewed. The broad observational facts and empirical phenomenological relations of the GRB prompt emission and afterglow are outlined. A well-tested, successful fireball shock model is introduced in a pedagogical manner. Several important uncertainties in the current understanding of the ...

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Inflammatory Signals Induce AT2 Cell-Derived Damage ...

2020-8-3 · Choi et al. show that inflammatory signals play a crucial role during alveolar regeneration after injury. They define stepwise differentiation trajectories for AT2 cells into AT1 cells via damage-associated transient progenitors (DATPs) and find that unresolved inflammation stalls transition of DATPs into mature AT1 cells.

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Pharmaceutics | Free Full-Text | Circulating Tumour Cells ...

2021-11-5 · Designing optimal (neo)adjuvant therapy is a crucial aspect of the treatment of non-small-cell lung carcinoma (NSCLC). Standard methods of chemotherapy, radiotherapy, and immunotherapy represent effective strategies for treatment. However, in some cases with high metastatic activity and high levels of circulating tumour cells (CTCs), the efficacy of standard treatment methods is insufficient ...

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Lenvatinib for hepatocellular carcinoma: From preclinical ...

2020-8-1 · Lenvatinib, a multi-target tyrosine kinase inhibitor (TKI), is an emerging first-line therapy for hepatocellular carcinoma (HCC). Its application has changed the status of sorafenib as the only first-line TKI treatment for HCC for more than a decade.

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Molecular classification reveals the diverse genetic and ...

1. Introduction. Globally, gastric cancer (GC) is the fifth most common tumor and the third leading cause of mortality .GC affects China the most; it contributes to 42.6% of global incidence and 45% of GC-related death and has the second leading incidence among all malignancies, .Helicobacter pylori infection is the most important pathogenic factor of GC.

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2021-11-15 · 11-11. 2021... 11-10. 2021. 11-04. 2021. 10-30. 2020-2021. ...

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JM-209 3.9±0.4 93±3 0.5 0.15±0.03 3 7 8-10 15 800 JM-300 4.7±0.3 95±3 0.17±0.03 2 JM-305 4.7±0.3 93±3 3 8 JM-320 5.5±0.3 90±3 0.2±0.05 20 600 JM-209P

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Cureus | Reduced Susceptibility and Resistance to ...

2021-10-20 · Staphylococcus aureus is a Gram-positive bacterium causing a wide range of infections ranging from cutaneous infections to endocarditis and bacteremia. Beta-lactamases such as penicillin and, subsequently, methicillin have been used in the treatment of S. aureus infections. With the emergence of methicillin-resistant Staphylococcus aureus (MRSA), vancomycin, a bacterial cell wall …

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sacB.pdf

2017-6-3 · sacB.pdf,590 2008,22 (5) :590~594 J ournal of N uclear Agricultural Sciences ( ) :10008551 2008 0559005 sacB 1 1,2 1 1 1 ...

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Measurement of Reactive Oxygen Species, Reactive …

Introduction. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are produced in virtually all eukaryotic cells. These molecules regulate several physiological processes including proliferation, migration, hypertrophy, differentiation, cytoskeletal …

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2020-8-28 · : ; ; ; . :, (acute pancreatitis, AP). AP. : ...

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Terahertz wave interaction with metallic nanostructures

2018-3-9 · Understanding light interaction with metallic structures provides opportunities of manipulation of light, and is at the core of various research areas including terahertz (THz) optics from which diverse applications are now emerging. For instance, THz waves take full advantage of the interaction to have strong field enhancement that compensates their relatively low photon energy. As the THz ...

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Successive Free-Radical C(sp2)–C(sp2) Coupling Reactions ...

2021-9-20 · Conclusion. Our study has proposed a free-radical C (sp 2 )–C (sp 2) coupling reaction to form predominately few-layer graphene (62.5%), as well as single- (15%) and bi-layer (22.5%) structures, through a reaction between HBB and metallic Na ( Supporting Information Tables S10 ). The reaction proceeds via successive C–C coupling processes ...

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Brain circuits for pain and its treatment

2021-11-11 · Pain is a multidimensional experience with sensory-discriminative, affective-motivational, and cognitive-evaluative components. Pain aversiveness is one principal cause of suffering for patients with chronic pain, motivating research and drug development efforts to investigate and modulate neural activity in the brain''s circuits encoding pain unpleasantness.

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Frontiers | Reactive oxygen species (ROS) and response of ...

Reactive oxygen species (ROS) were initially recognized as toxic by-products of aerobic metabolism. In recent years, it has become apparent that ROS plays an important signaling role in plants, controlling processes such as growth, development and …

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The Role of DLLs in Cancer: A Novel Therapeutic Target | OTT

Introduction. Notch is an evolutionary-conserved signaling system that regulates cell fate through local cell–cell interactions. In mammals, four Notch receptors (Notch1–4) and five Notch ligands (Delta-like 1, 3, 4 and Jagged 1–2) are expressed ().Notch receptors …

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α-Synuclein Aggregation and Modulating Factors | …

2012-12-6 · Anderson JP, Walker DE, Goldstein JM, de Laat R, Banducci K, Caccavello RJ, Barbour R, Huang J, Kling K, Lee M, Diep L, Keim PS, Shen X, Chataway T, Schlossmacher MG, Seubert P, Schenk D, Sinha S, Gai WP, Chilcote TJ (2006) Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body ...

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Kunshan GAO

2003-1-2 · Journal of Photochemistry and Photobiology B: Biology 104 (1): 320-325. Xu Kai, Gao Kunshan*, Villafañe ia E, Helbling E Walter. 2011. Photosynthetic responses of Emilianiahuxleyi huxleyi to UV radiation and elevated temperature: roles of calcified coccoliths. Biogeosciences 8: 1441-1452. *. 2011.

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Photosystem II reaction centre quenching: mechanisms …

2008-9-27 · Dissipation of excess absorbed light energy in eukaryotic photoautotrophs through zeaxanthin- and ΔpH-dependent photosystem II antenna quenching is considered the major mechanism for non-photochemical quenching and photoprotection. However, there is mounting evidence of a zeaxanthin-independent pathway for dissipation of excess light energy based within the PSII reaction …

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Single-cell analysis of ploidy and the transcriptome ...

2021-10-7 · Megakaryocytes (MKs), the platelet progenitor cells, play important roles in hematopoietic stem cell (HSC) maintenance and immunity. However, it is not known whether these diverse programs are executed by a single population or by distinct subsets of cells.

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MECHE PEOPLE: Michael Triantafyllou | MIT Department of ...

2007-10-5 · MIT''s Department of Mechanical Engineering (MechE) offers a world-class education that combines thorough analysis with hands-on discovery. One of the original six courses offered when MIT was founded in 1865, MechE''s faculty and students …

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Role of the Extrinsic Pathway of Blood Coagulation in ...

2007-6-7 · Figure 1. Formation of a clot at the site of blood vessel injury. In a healthy individual, TF expressed by vascular smooth muscle cells, pericytes, and adventitial fibroblasts in the vessel wall is physically separated from its ligand FVII/FVIIa by the …

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Reactive Oxygen Species, Oxidative Damage, and ...

Reactive oxygen species (ROS) are produced as a normal product of plant cellular metabolism. Various environmental stresses lead to excessive production of ROS causing progressive oxidative damage and ultimately cell death. Despite their destructive activity, they are well-described second messengers in a variety of cellular processes, including conferment of tolerance to various environmental ...

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Histone acetylation and the role of histone deacetylases ...

2020-8-13 · Histone acetylation is a critical epigenetic modification that changes chromatin architecture and regulates gene expression by opening or closing the chromatin structure. It plays an essential role in cell cycle progression and differentiation. The human endometrium goes through cycles of regeneration, proliferation, differentiation, and degradation each month; each phase requiring strict ...

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John Mattick | School of Biotechnology and Biomolecular ...

2021-11-3 · John Mattick is SHARP Professor of RNA Biology at UNSW Sydney. He was recently previously Executive of Genomics England (2018-2019), and Director of the Garvan Institute of Medical Research in Sydney (2012-2018), where he established one of the first HiSeq X10 sequencing and clinically accredited genome analysis facilities.

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Kunshan GAO

2003-1-2 · Journal of Photochemistry and Photobiology B: Biology 104 (1): 320-325. Xu Kai, Gao Kunshan*, Villafañe ia E, Helbling E Walter. 2011. Photosynthetic responses of Emilianiahuxleyi huxleyi to UV radiation and elevated temperature: roles of calcified coccoliths. Biogeosciences 8: 1441-1452. *. 2011.

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